A 52 yr old female ,homemaker by occupation
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CASE :
CASE :
A 52 year old female,house wife resident of narketpally came to the causality in a drowsy state
She was apparently asymptomatic 1 week back,when she sustained an injury to the left LL(shin according to attenders but wound not visible outside -outside x-rays normal ),after which she developed pain and edema ,she was treated outside with pain killers ,had restricted movements and hence did not move much and lied on bed most of the time ,walked with support and gradually the swelling got decreased to some extent . 5 days later she again visited RMP as her appetite was decreased and also associated with generalised weaknesses and left lower limb pain and also hip( localisation not possible )for which pt was given IV fluids and pain killers.
This morning after eating ,she had sudden onset of around 10-15 vomiting episodes with nausea then she suddenly became drowsy ,while she was being shifted here,there is irrelevant talk and pt was incoherent.
On presentation, pt was unconscious with
E1V1M4 to E1V1M1
Past history :
No H/o diabetes, hypertension,asthma epilepsy,TB
No similar complaints in the past
No history of any surgeries or blood transfusions
Personal history :
Diet - Veg
Appetite - decreased
Sleep - adequate
Bowel and bladder movements : Regular
No known allergies
No history of alcohol consumption or smoking
On examination:
Pt is stupourous ,withdrawal from pain
Febrile to touch:100°F
PR: 86bpm
BP: 130/70 mmHg
RR: 24
CVS: S1, S2 heard
RS: BAE present ,end inspiratory wheeze in all areas ,
Spo2: 96%on room air
P/A: obese ,non tender ,bowel sounds sluggish
CNS:
Pupils - right side -NS RL
Left side - post cataract surgery r/n to light
Gag present
Tone : normal b/l
Reflexes
Lt. Rt
B. 2+. 2+
T. 2+. 2+
S. 2+. 2+
K 2 +. 2+
A. 2+. 2+
P. Upgoing. Upgoing
Provisional diagnosis:
Altered sensorium under evaluation secondary to hyponatremia( euvolemia)?SIADH
Sepsis secondary to ?cellulitis ? Typhoid
with complete right bundle branch block
Investigations :
RFT :
Urea - 15
Creatinine - 0.6
Uric acid - 2
Calcium - 8.6
Phosphorus - 3.2
Na+ : 118
K+ : 3.8
Cl- : 76
LFT :
TB : 0.88
DB : 0.20
AST : 26
ALT : 13
ALP : 177
TP : 5.5
ALB : 3.1
A/G : 1.33
Serum osmolality :
Serum sodium @ 10pm
Urinary electrolytes :
ECG :
CHEST X RAY :
MRI BRAIN :
TREATMENT :
1) Propped up position
2) IVF 3% Nacl @10 ml/hr
3) Ryles catheterization
4)Foley's catheterization
5)Inj.Piptaz 4.5 gm /IV/BD
6) RT feeds : 100ml water 2nd HRLY
50 ml milk 4rth HRLY
Day 2 of admission :
Pt is stupourous ,withdrawal from pain
Febrile to touch:100°F
PR: 86bpm
BP: 130/70 mmHg
RR: 24
CVS: S1, S2 heard
RS: BAE present ,end inspiratory wheeze in all areas ,
Spo2: 96%on room air
P/A: obese ,non tender ,bowel sounds sluggish
CNS:
Pupils - right side -NS RL
Left side - post cataract surgery r/n to light
Gag present
Tone : normal b/l
Reflexes
Lt. Rt
B. 2+. 2+
T. 2+. 2+
S. 2+. 2+
K 2 +. 2+
A. 2+. 2+
P. Upgoing. Upgoing
Diagnosis:
Altered sensorium under evaluation secondary to hyponatremia( euvolemia)?SIADH
Sepsis secondary to ?cellulitis ? Typhoid
with complete right bundle branch block
Investigations :
RFT :
Urea - 13
Creatinine - 0.6
Uric acid - 2
Calcium - 8.5
Phosphorus - 3.5
Na+ : 128
K+ : 3.9
Cl- : 90
ABG :
Electrolytes @ 2pm :
Na+ : 123
K+ : 3.9
Cl- : 85
Electrolytes @10 pm :
Na+ : 123
K+ : 3.9
Cl- : 85
Pt developed bed sore on her right
buttock :
Treatment :
1) Propped up position
2) IVF 3% Nacl @10 ml/hr
3) Inj.PANTOP 40 mg PO/OD
4)Inj.Piptaz 4.5 gm /IV/TID
5) Nebulization with budecort @ 8th HRLY and
Asthalin @12th HRLY
6) RT feeds : 100ml water 2nd HRLY
50 ml milk 4rth HRLY
Day 3 of admission :
Still in altered sensorium
And attendant complaints of her having on and off fever episodes and no improvement in sensorium since admission
O -
However her GCS has gone up from E1M1V1 to E2V1M1
RR - 35 cpm
PR - 124bpm
BP- 120/70mmhg
Temp - 101 F
Spo2 - 98%on 15L RA
CNS -
E2M1V1
Pupils -
Bilaterally reacting to light
Left post cataract surgery
Hypotonia + in all 4 limbs
Reflexes-
Bilateral biceps +
Plantars - Mute
Corneal and conjunctival reflexes +
No meningeal signs
Lungs - Bilateral inspiratory crepts in all Lung fields
And expiration wheeze in all Lung fields
Cvs - S1,S2+
Per Abdomen - soft
Bowel sounds +
A -
Altered senorium secondary to ? Hyponatremia
Sepsis secondary to ? cellulitis
? Typhoid
With complete RBBB
P -
LP was done will be updating shortly
Continuing her on
Inj 3% NACL @ 10ml/hour
Inj Pantop 40mg IV OD
Inj Piptaz 4.5 gm/IV/TID
Neb with budecort 8th hourly and Asthalin 12 hourly
RT feeds - 100ml milk and 50ml free water 2nd hourly
Tab Dolo 650mg sos
Hemogram :
Hb - 11.6
TLC : 46500
Plt : 39900
RBC : 4.56
ABG @ 6am :
Chest xray :
ECG :
ABG @ 12pm :
After lp,csf was sent for analysis :
Volume : 1ml
Appearance : clear
Color : slightly reddish
TC - 436 (corrected WBC count )
Dc - 90% neutrophils ,10% lymphocytes
RBC - 14650
Others : nil
Awaiting cytology reports
Csf sugar : 25
Csf protein : 29
Csf chloride : 116
RBS : 85
Electrolytes @6pm :
Na - 122
K - 4.2
Cl - 80
Day 4 :
52 year old woman,
ICU bed 1
Still in altered sensorium
And attendant complaints of her having on and off fever episodes
no improvement in sensorium since admission
O -
GCS E2V1M1
Pt is on mechanical ventilation
Simv - vc mode
Tv - 400 ml
PEEP - 5 cm of h20
FiO2 - 30%
RR - 40 cpm
PR - 94bpm
BP- 110/60mmhg
Temp - 37.3 C
Spo2 - 98%on 15L RA
CNS -
E2M1V1
Pupils -
Bilaterally reacting to light
Left post cataract surgery
Hypotonia + in all 4 limbs
Reflexes-
Bilateral biceps +
Plantars - Mute
Corneal and conjunctival reflexes +
No meningeal signs
Lungs - Bilateral inspiratory crepts in all Lung fields
And expiration wheeze in all Lung fields
Cvs - S1,S2+
Per Abdomen - soft
Bowel sounds +
A -
Altered senorium secondary to ? Hyponatremia
Sepsis secondary to ? cellulitis ? Pyogenic meningitis
? Typhoid
With complete RBBB
P -
Inj.Dexa 4mg iv/ bd
Inj. Ceftriaxone 2 gm iv. Bd
Inj Pantop 40mg IV OD
RT feeds - 100ml milk and 50ml free water 2nd hourly
Investigations :
Hb - 11
TLC - 52500
Pcv - 29.2
Plt - 3.48
TB - 3.46
Db - 0.63
AST - 1036
Alt - 530
TP - 5.3
Alb - 2.73
A/g - 1.06
ABG :
pH - 7.527
pCo2 - 13.7
PO2 - 106
HCo3 - 17.4
Rft :
Urea - 137
Creat - 2.8
uric acid - 11.5
Ca- 10.2
Phosphate - 11.2
Na - 119
K - 4.3
Cl - 75